Michele Garibbo

Centre for Genomic Regulation

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Ciao!

I am a Deep Learning Scientist in AI for Protein Design led by Noelia Ferruz at the Centre for Genomic Regulation. Previously, I was a Postdoctoral Research Associate in Neuroscience and Machine Learning in the Neural & Machine Learning Group at the University of Oxford. I completed my PhD in Machine Learning and Neuroscience at the University of Bristol under the supervision of Laurence Aitchison (primary), Casimir Ludwig, and Nathan Lepora.


Research interests

My research focuses on end-to-end training of autoregressive protein language models, with particular emphasis on large-scale pretraining and reinforcement learning–based alignment. I also explore genomic foundation models (e.g., Evo2) and their applications to de novo design of functional elements such as piggyBac transposons.

Previously, I worked on reinforcement learning applications to understanding motor learning in neuroscience, as well as deep RL research aimed at improving value estimation in Actor–Critic algorithms.

More broadly, I am interested in how machine learning and computational models can provide principled frameworks for understanding and designing biological systems.